|Episode name pun on: Birthday Bash (or, party)|
|Airdate:||August 20, 1999|
"Too Pooped to Puff"
While in prison The Powerpuffs mortal enemies in jail come up with their own plans to destroy the girls. Later on, Him tries a plan of his own- an evil pinata monster that is trying to destroy the Powerpuff Girls' neighborhood!
While in prison, Mojo Jojo, Princess Morbucks, and the Amoeba Boys all come up with their own plans to destroy the Girls. In the morning, the Girls are dying to open the presents when the time has come for, the Girls to open their gifts they rush to choose a present, and, not realizing that gift is from Mojo, they open it and a giant robot comes out. It destroys everything, but the girls get rid of it and Mojo's plan fails. Afterwards, they choose another gift and it's from Princess Morbucks, but there is nothing in it but a target. The girls see a giant rocket flying toward it and the girls destroy it at once! The Princess's plans fails. Next, the Amoeba Boys present is chosen by the girls and there are dolls in it. Later HIM tries a plan of his own.
- The Powerpuff Girls
- Mojo Jojo
- Princess Morbucks
- The Amoeba Boys
- Professor Utonium
- The Mayor of Townsville
- Ms. Sara Bellum
- Ms. Keane
- Rainbow the Clown/Mr. Mime (as his normal self)
- The part where Princess' birthday present to the girls was a bomb is referenced in 'Twas the Fight Before Christmas.
- Blossom isn't wearing a party hat like her sisters because of her bow.
- This is one of the few episodes that HIM does not frown at all. The other being Speed Demon
- The gifts given by the villains are
- Mojo Jojo- A giant elastic robot
- Princess Morbucks- A bull's eye and a giant missile
- Amoeba Boys- Voodoo dolls that resemble the girls
- HIM- A piñata (the strangest gift the girls did not notice and was later enlarged and brought to life by the demon)
- Rainbow the Clown and the bleach truck driver from Mime for a Change appear again in this episode.
- Star Wars - The Princess Leia appears in the background of the party.
- The Simpsons - When Mojo's plan fails, Princess Morbucks laughs like Nelson Muntz.
- When the girls hold up Mojo Jojo's present, Bubbles loses her party hat, but regains it when Stanley announces they're about to open the gift.
- The card that came with the Amoeba Boys present says "from your friends", but Blossom reads it as "from your bestest pals". This may be intended.